In the pursuit of defying aging, one name stands out prominently – Dr. David Sinclair. As an esteemed Harvard geneticist, Dr. Sinclair has captivated the world with his groundbreaking research on longevity and aging. His latest anti-aging protocol reveals a meticulously curated selection of supplements and drugs aimed at decelerating the aging process. Today, we delve into the updated 2024 version of Dr. Sinclair's supplement regimen, offering a glimpse into the secrets of extended longevity.
Dr. Sinclair's Updated Supplement Regimen
Fisetin: 500 mg
At the forefront of his protocol lies Fisetin – a powerful senolytic agent that targets senescent cells, the culprits behind various age-related ailments. Paired with Quercetin, this duo forms a potent combination that promises to extend healthspan and lifespan.
Lipoic Acid: 300 mg
Lauded for its antioxidant properties, lipoic acid plays a vital role in combating oxidative stress, a major contributor to aging. By incorporating this supplement, Dr. Sinclair fortifies his body against the ravages of time.
Fish Oil (EPA/DHA): ?
Although Sinclair did not mention his specific fish oil dosage, several longevity experts and physicians, including Dr. Andrew Huberman and Dr. Peter Attia, mentioned they take 2 g of EPA and around 1.5 g of DHA.
Rich in omega-3 fatty acids, fish oil offers a myriad of benefits for heart health, inflammation reduction, and cognitive function. Although the exact dosage remains unspecified, its inclusion underscores the importance of essential fatty acids in an anti-aging regimen.
L-Taurine: 2 g
Known for its cardiovascular and metabolic support, L-Taurine serves as a valuable addition to Dr. Sinclair's protocol, promoting overall well-being and longevity.
Nicotinamide Mononucleotide (NMN): 1 g
A cornerstone of his regimen, NMN bolsters cellular energy production, DNA repair mechanisms, and longevity pathways. With a focus on bioavailability and efficacy, Dr. Sinclair upholds NMN as a pivotal component for aging gracefully.
Resveratrol: 1 g
Harnessing the longevity benefits of red wine, resveratrol mimics the effects of caloric restriction, a proven strategy for extending lifespan. By integrating resveratrol into his daily routine, Dr. Sinclair taps into its vast therapeutic potential.
Spermidine: 1-2 mg
Emerging as a key player in autophagy and cellular rejuvenation, spermidine holds promise in counteracting age-related decline. Dr. Sinclair's inclusion of this compound signifies his commitment to exploring innovative pathways for longevity.
Vitamin D3: 4,000-5,000 IU
Essential for bone health, immune function, and neurotransmitter modulation, Vitamin D3 plays a critical role in maintaining overall vitality and resilience to aging.
Vitamin K2: 180-360 mcg
Working synergistically with Vitamin D3, Vitamin K2 regulates calcium metabolism, supports cardiovascular health, and promotes bone strength. Dr. Sinclair's dosage range reflects the meticulous balance he strives to achieve in his regimen.
Trimethylglycine (TMG): 500-1,000 mg
As a methyl donor, TMG aids in methylation processes crucial for gene expression, detoxification, and cellular repair. Its presence underscores Dr. Sinclair's holistic approach to anti-aging interventions.
Low-Dose Aspirin: 83 mg
Recognized for its anti-inflammatory and cardioprotective effects, low-dose aspirin complements Dr. Sinclair's regimen by addressing age-related inflammation and cardiovascular risks.
Metformin: 1 g
Originally prescribed for diabetes management, metformin has garnered attention for its potential anti-aging properties, impacting various pathways associated with longevity and healthspan.
Rapamycin: ?
An intriguing addition to Dr. Sinclair's arsenal, rapamycin modulates cellular processes related to aging, metabolism, and immune function. While the exact dosage remains undisclosed, its inclusion highlights the multifaceted approach Dr. Sinclair adopts in combating aging.
Sinclair’s rapamycin dose is unknown, but in an interview he had with longevity entrepreneur Dr. Peter Diamadis, Diamadis states that he takes 6 mg of rapamycin once a week.
Through Dr. David Sinclair's meticulously honed anti-aging protocol, a glimpse into the intricate landscape of longevity emerges. By embracing the latest scientific insights and refining his supplement stack, Dr. Sinclair continues to pave the way for a future where age may be but a number. As we unravel the secrets of aging alongside Dr. Sinclair, we embark on a transformative journey towards a healthier, rejuvenated existence.
Remember, always consult with a healthcare professional before incorporating any new supplements or medications into your regimen.
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