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The Impact of Ca-AKG on Lifespan and Healthspan


Wouldn't it be incredible if we could pause the relentless march of time and maintain the vigor and vitality of our youthful years as we age? While turning back the clock remains a fantasy, integrating Ca-AKG into our routines could be the key to enhancing both our lifespan and health span, enabling us to gracefully navigate the process of aging with optimal well-being.


Unveiling Ca-AKG


Ca-AKG, formally known as Calcium Alpha-Ketoglutarate, is a naturally occurring compound within our bodies. Initially, the body efficiently produces AKG until around the age of 40, after which the production diminishes significantly. Research demonstrates that by the age of 80, AKG levels plummet to just 10% of the levels found at 40.


As we grow older, AKG plays a crucial role in cellular energy production, supplying energy to our cells and fortifying them during our developmental years. Besides fueling cellular processes, AKG supports muscular health, digestion, kidney function, and bone tissue construction. The natural decline of AKG production renders us more vulnerable to age-related ailments and frailty.


Recently, Alpha-Ketoglutarate (AKG) has been introduced as a potential anti-aging metabolite that can control several functions in organisms, thereby increases longevity and improves health span. Unlike other synthetic anti-aging drugs, AKG is one of the metabolites of the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle, and synthesized in the body. It plays a crucial role in the cell energy metabolism, amino acid/protein synthesis, epigenetic regulation, stemness and differentiation, fertility and reproductive health



What is the difference between regular Alpha-Ketoglutarate (AKG) versus Calcium Alpha-Ketoglutarate (Ca-AKG)



Most Alpha-Ketoglutarate supplements contain plain Alpha-Ketoglutarate.

However, scientists believe that the calcium form of Alpha-Ketoglutarate, namely Calcium Alpha-Ketoglutarate (Ca-AKG), is significantly better than regular/plain Alpha-Ketoglutarate.


Calcium Alpha-Ketoglutarate can have additional beneficial effects compared to Alpha-Ketoglutarate. One reason for this is that Ca-AKG is more slowly absorbed in the gut and released into the bloodstream, so it can work for longer in the body. This makes sense, given Alpha-Ketoglutarate is an important metabolite and ideally it should be present in our body at sufficiently high levels for as long as possible. 


Most supplements on the market contain only plain Alpha-Ketoglutarate (AKG), not Calcium Alpha-Ketoglutarate (Ca-AKG). Also, their dose of Alpha-Ketoglutarate is often too low.





Embracing the Benefits of Ca-AKG



Prolonged Lifespan and Enhanced Quality of Life


Studies indicate that Ca-AKG intake could potentially extend lifespan by up to 12%. While aging-related health decline might be inevitable, supplementing with Ca-AKG seems promising in managing this decline by mitigating morbidities associated with aging.



Enhanced Metabolism


Ca-AKG has been shown to enhance amino acid metabolism and lower ammonia levels in cells, thereby reducing hyperphosphatemia. A robust metabolism is paramount for healthy aging as it sustains overall bodily health and potentially


Enhancing Skin Health and Appearance


Ca-AKG positively impacts skin health. It supports collagen synthesis, essential for maintaining skin elasticity and firmness. The compound’s antioxidant properties help combat free radicals which contribute to skin aging. By reducing oxidative damage, Ca-AKG helps preserve a youthful appearance and improves overall skin health.



Supporting Bone Health


Bone health benefits from Ca-AKG as well. It aids in calcium absorption and bone mineralization, crucial for maintaining strong bones. Research by Riedel et al. (1996) found that Ca-AKG dietary supplement improved plasma arginine concentrations, which support bone metabolism. By enhancing bone density and skeletal muscle, and reducing bone resorption, Ca-AKG plays a vital role in sustaining skeletal strength as we age.



Calcium AKG for Athletes


Ca AKG benefits vary, but calcium for athletes, especially when combined with AKG, has enormous potential and should definitely be considered for all athletes and fitness enthusiasts.


In Ca-AKG studies, it has been found to fuel our cells, generating energy so that we can function and exercise at our peak. This is due to its role in the Krebs cycle, which is needed for energy production and metabolic function. For those of us who are looking to improve our physical performance, it’s a great supplement to actually help us focus on our fitness.


Due to its function in protein synthesis, it supports muscle health and recovery as it prevents muscle protein loss, and it also helps us maintain a healthy body weight. Not only that, but it also protects our cardiac tissues and helps to maintain our cardiovascular health, making it a fantastic fitness supplement for people who want to improve their workout performance and muscle recovery, or just active individuals in general!



Guidance on Usage


For those considering integrating Ca-AKG into their regimen, the dosage and timing are pivotal:



How to Take Calcium AKG?

 

  • Start Slow: Begin with a lower dosage, then gradually increase it. For example, with Green As Nature’s Ca-AKG, start with one capsule daily, then increase to two after a few weeks.

  • Timing Matters: For better absorption, take it away from high-fiber meals and iron supplements.

  • With Vitamins: It might help to take your Ca-AKG with a multivitamin as vitamin K and vitamin D help improve calcium absorption, ideally at midday for sunlight exposure.

  • Take with Food: Have it with a meal at midday to aid digestion.



Ca-AKG Side Effects



  • Generally Safe: There are no significant side effects or interactions from AKG supplements but stop taking them immediately if you experience any adverse effects.

  • Speak with Your Doctor: Before adding any new supplement to your diet, speak with your medical professional, especially if you are pregnant, breastfeeding or have any medical conditions.

  • Follow Recommendations: Stick to recommended dosages and stay hydrated.

  • Choose Wisely: Always buy from reputable brands like Green As Nature, with a manufacturer certificate of analysis.

  • Safe Use: AKG is generally safe for up to three years but avoid it during pregnancy.

 


Ca-AKG Dosage



  • There’s currently no recommended dosage of AKG, but, according to studies:


    • Recommended Daily: Between 1000 and 1300mg per day.




Anticipated Outcomes


Upon incorporating Ca-AKG into your routine diligently, you can expect a range of advantages, including improved cellular energy production, enhanced muscular health, and potentially mitigating age-related frailty. Ultimately, embracing Ca-AKG in a holistic approach to health and wellness may pave the way for a more vibrant and fulfilling aging journey.


In conclusion, while halting the aging process remains beyond our reach, optimizing our health span and lifespan through the integration of Ca-AKG offers a promising strategy toward aging with strength and vitality. By understanding the significance of AKG in our bodies and the potential benefits of supplementing with Ca-AKG, we can take proactive steps towards achieving optimal health as we navigate the passage of time.


Green As Nature sells Pure Ca-AKG 1000mg capsules without any filler, binders or additives, or you can look at AgeLess X7 supplement which contains Ca-AKG in combination with other 6 health supplements celebrated in the anti-aging segment, for more information go to www.greenasnature.com

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